The Poison and the Dose

The Poison and the Dose

The debate about threshold values for chemical residues in water and food is often shaped by misunderstandings and emotions. Few topics show as clearly how far perception and science can drift apart. But what do limit values really mean? In autumn 2025, the Agricultural Policy Podcast and swiss-food.ch will explore our relationship with limits and risk in a five-part series. The highlight was a live podcast recording on November 5 at Bogen F in Zurich.

Wednesday, October 8, 2025

Limit values are intended to protect society from excessive exposure to potentially harmful substances. Thanks to advances in analytics, even the tiniest traces can now be detected. This often leads to differing interpretations of measurement results and their significance. The line between honest education, alarmism, and trivialization is a fine one.

It’s the dose that makes the poison – for both natural and synthetic substances. Residues alone do not indicate danger. At the same time, «natural» substances enjoy enormous trust, even when they can be toxic – mushroom toxins are a prime example.

How difficult it is to strike a balance between safety-mindedness and practical reason is aptly summed up by Roman Mazzotta, Country Head of Syngenta Switzerland: «One of the most dangerous things you can do is drive a car. There are distance regulations: on the motorway, the required distance to the next car is 60 metres. That’s the ‘limit value’. For chemical substances that are neither DNA-damaging nor carcinogenic, a hundredfold safety margin is added to that limit value. Translated to road traffic, that would mean keeping a distance of six kilometres from the next car. On which motorway in Switzerland could you still drive with such distance rules? It’s the same sense of proportion I’m talking about when it comes to limit values in water.»

In five engaging episodes, experts from toxicology, industry, government, and agriculture discuss what safety really means and the role that limit values play.


The podcast series


October 11 – Dr. Angela Bearth
The Agricultural Policy Podcast with Dr. Angela Bearth on perceived dangers and real risks. Angela Bearth holds a PhD in Social and Health Psychology from the University of Zurich and works as a senior social scientist at the Swiss Centre for Applied Human Toxicology (University of Basel).

Here is Episode 1 with Dr. Angela Bearth (translated with AI)

October 18 – Dr. Lothar Aicher
The agricultural policy podcast with Dr Lothar Aicher on residues in our everyday lives. Lothar Aicher is a chemist who initially worked in pharmaceutical research and later in the chemical/agricultural industry as a human safety assessment manager. Since 2010, he has been working as a toxicologist at SCAHT (Swiss Centre for Applied Human Toxicology).

Here is Episode 2 with Dr. Lothar Aicher (translated with AI)

October 25 – Dr. Michael Beer
The agricultural policy podcast with Dr Michael Beer on reports and warnings from the authorities. Michael Beer studied food engineering and obtained his doctorate at the Institute of Human Nutrition at ETH Zurich. Since 2014, he has been head of the Food and Nutrition Division of the Federal Food Safety and Veterinary Office (FSVO) and is deputy director of the FSVO.

Here is Episode 3 with Dr. Michael Beer (translated with AI)


November 1st – Christine Badertscher

The agricultural policy podcast with National Councillor Christine Badertscher on the political debate surrounding the setting of limit values. Christine Badertscher grew up on a farm in the Emmental region. She studied environmental engineering in Wädenswil and agricultural sciences at the HAFL. She has been a National Councillor for the Green Party in the canton of Bern since 2019.

Here is Episode 4 with Christine Badertscher (translated with AI)

The Agrarpolitik podcast is available on all major platforms. Click here to see the overview. Here you can listen to the latest episodes.

Kindly note:

We, a non-native editorial team value clear and faultless communication. At times we have to prioritize speed over perfection, utilizing tools, that are still learning.

We are deepL sorry for any observed stylistic or spelling errors.

Related articles

Facts about drinking water and limit values
Knowledge

Facts about drinking water and limit values

'Pure' water is either a tasteless distillate or a selling point. As natural products, neither tap water nor branded water is 'pure'. However, both can be drunk without hesitation.

"Swiss water is in a bad way."
Knowledge

"Swiss water is in a bad way."

That's not actually true. Our surface waters, groundwater and drinking water are in very good condition. Our water quality tops international rankings. There cannot be any mention of poor Swiss water quality.

Chlorothalonil – communication with cost consequences
Media

Chlorothalonil – communication with cost consequences

Once upon a time there was a canton in Seldwyla. In order to better regulate access traffic to a larger town, the canton decided to install so-called "gatekeeper systems" on the access roads, i.e. traffic lights that stop private traffic and thus access to the town by means of red lights when traffic in the town itself comes to a standstill.

Residues, thresholds, trust – looking calmly behind the headlines
Knowledge

Residues, thresholds, trust – looking calmly behind the headlines

In this conversation with toxicologist Lothar Aicher, the discussion focuses on how residues enter the body, how their potential harm is assessed, and what role modern analytical methods play.

Hazard is not the same as risk: how we understand – and should understand – threshold values
Knowledge

Hazard is not the same as risk: how we understand – and should understand – threshold values

In this episode of the podcast, risk researcher Angela Bearth discusses residues and threshold values in food – a topic often debated emotionally. In public discussions, threshold values tend to dominate, while the complex challenges of agriculture are rarely considered. Studies show, however, that once these relationships are explained and solutions are addressed, people respond in a more differentiated way.

PFAS, trade-offs and responsibility – how politics and agriculture find solutions
Knowledge

PFAS, trade-offs and responsibility – how politics and agriculture find solutions

In this episode of the joint series by Agrarpolitik – der Podcast and swiss-food.ch, National Councillor Christine Badertscher discusses how residues and threshold values are debated in Parliament.

Thresholds, approvals, responsibility – how plant protection products are really assessed
Knowledge

Thresholds, approvals, responsibility – how plant protection products are really assessed

Threshold values are often at the centre of public debate – yet in reality they are only a small part of a much broader risk assessment system. Dr Michael Beer, Head of the Food and Nutrition Division at the Federal Food Safety Office, provides clarity.

More contributions from Knowledge